Gwenwyneg plaladdwyr organoffosfforws

Gall gwenwyndra pob rhywogaeth fod yn wahanol, mae'r rhan fwyaf ohonynt yn wenwynig iawn ac yn wenwynig iawn, ac mae rhai yn wenwynig iawn.

Mae rhai mathau yn cael effaith wenwynig pan gânt eu defnyddio mewn cyfuniad, megis cymysgeddau o malathion a trichlorfon, trichlorfon ac azinphos.

Gellir trawsnewid rhai mathau i gynyddu gwenwyndra. Er enghraifft, mae gwenwyndra 1605 yn cynyddu ar ôl ocsideiddio, ac mae triclorfon yn cael ei drawsnewid yn dichlorvos mewn datrysiad alcalïaidd, sy'n fwy gwenwynig.

Organophosphorus pesticides (organophosphate pesticides) form phosphorylated cholinesterase with cholinesterase in the body. The activity of cholinesterase is inhibited, so that the enzyme cannot decompose acetylcholine, resulting in excessive accumulation of acetylcholine in tissues. Overexcites cholinergic nerves, causing muscarinic, nicotinic, and central nervous system symptoms. Phosphorylated cholinesterase generally "ages" after about 48 hours and is not easy to recover.

Some ester hydrocarbyl and aromatic hydrocarbyl phosphate compounds still have delayed neurotoxicity, which is caused by organophosphorus pesticides inhibiting neuropathy target esterase (neurotoxic esterase) in vivo and causing it to "age", causing delayed neurotoxicity. Neuropathy. This toxic effect has nothing to do with cholinesterase activity.

Mae plaladdwyr organoffosfforws ar ffurf micro-gapsiwlau sy'n cael eu rhyddhau'n barhaus yn para am gyfnod hirach o weithredu.